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ORIGINAL ARTICLE
Year : 2010  |  Volume : 1  |  Issue : 3  |  Page : 163-166

Antihyperglycemic activity of Tectona grandis Linn. bark extract on alloxan induced diabetes in rats


1 Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha - 402 102, India
2 Department of Pharmacology, Mahatma Gandhi Mission Hospital, Aurangabad - 431 001, Maharashtra, India

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D L Jaybhaye
c/o Ramesh Shripatrao Patil, Plot no. 17 Flat No. 5, Vidyanagar Near 7 Hill, Aurangabad - 431 001, Maharashtra
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DOI: 10.4103/0974-7788.72488

PMID: 21170208

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Tectona Grandis Linn.(saag - tick wood), an indigenous medicinal plant, has a folk reputation among the Indian herbs as a hypoglycemic agent. The present study was carried out to evaluate the anti-hyperglycemic effect of T. grandis Linn. bark extract in control and alloxan-diabetic rats. Oral administration of the bark suspension of T. grandis (2.5 and 5 g/kg body wt.) for 30 days resulted in a significant reduction in blood glucose (from 250 ± 6.5 to 50 ± 2.5 mg/dL). Thus, the present study clearly shows that the T. Grandis Linn. bark extract exerts anti-hyperglycemic activity.


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