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| Year : 2011 | Volume
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| Issue : 1 | Page : 65 |
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| Authors' reply |
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Jyoti Sethi1, Mridul Yadav1, Sushma Sood1, Kiran Dahiya2, Veena Singh2
1 Department of Physiology, Pt. B.D. Sharma University of Health Sciences, Rohtak, Haryana, India
2 Department of Biochemistry, Pt. B.D. Sharma University of Health Sciences, Rohtak, Haryana, India
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| Date of Web Publication | 26-Jul-2011 |
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How to cite this article:
Sethi J, Yadav M, Sood S, Dahiya K, Singh V. Authors' reply. Int J Ayurveda Res 2011;2:65 |
Sir,
We are thankful for your interest in our article. [1]
The same dose of Tulsi was used in the previous studies showing the effect of Tulsi on sperm count. [2] LD 50 of Ocimum sanctum extract is 4.5 g/kg by oral route. [3] We have used 2 g of fresh leaves per day which is equal to ~ 0.8 g dry weight which is much less than the LD 50. We do not wish to create a scare regarding use of Tulsi but the study is a preliminary observation showing the effect of Tulsi on reproductive hormones. Further research is needed on extracts of Tulsi which cause this effect and potential use of Tulsi extracts in oral male contraceptives.
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| 1. | Sethi J, Yadav M, Sood S, Dahiya K, Singh V. Effect of Tulsi (Ocimum sanctum Linn) on sperm count and reproductive hormones in male albino rabbits. Int J Ayurveda Res 2010;1:208-10. 
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| 2. | Khanna S, Gupta SK, Grover JK. Effect of long term feeding of Tulsi (Ocimum sanctum L) on reproductive performance of adult albino rats. Indian J Exp Biol 1986;24:302-4.
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| 3. | Sembulingam K, Sembulingam P, Namasivayam A. Effect of Ocimum sanctum Linn on noise induced changes in plasma corticosterone level. Indian J Physiol Pharmacol 1997;41:139-43.
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Correspondence Address:
Jyoti Sethi
Department of Physiology, Pt. B.D. Sharma University of Health Sciences, Rohtak, Haryana
India
PMID: 21897652
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